arbetsgivarverket.se

Jobba Statligt

Postdoctoral Fellow in metabolic regulation of macrophages

  • Yrkesroll

    Immunolog

  • Anställning

    Heltid, 6 månader eller längre

  • Lön

    Fast månads- vecko- eller timlön

  • Publicerad

    29 augusti

  • Sök jobbet senast

    19 september

Om jobbet

The University of Gothenburg tackles society’s challenges with diverse knowledge. 47 500 students and 6 400 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

We are seeking a highly motivated, academically excellent and proactive Postdoctoral Researcher with a strong background in innate immunity to study the relation between the macrophage biology and metabolism, and to further develop this research area in the recently established Anetta Härtlova lab (https://wcmtm.gu.se/research-groups/hartlova-group).

 

Subject area description

Macrophages are key innate players driving inflammation, repair and resolution. Recently, metabolic state has been shown to be an important determinant for the switch between different macrophage phenotypes. Pro-inflammatory responses are in general dependent on glycolytic, rapid energy sources whilst resolution responses are more long lasting and generally dependent on oxidative lipid metabolism. In this project, we will investigate metabolic regulation of macrophages and how macrophage fitness contribute to the development of chronic diseases. This project is built on our recent work that unravel the role of macrophage scavenger receptor 1 (MSR1) in macrophage polarization (https://www.ncbi.nlm.nih.gov/pubmed/31028084).

Job assignments

The successful appointee will have the opportunity to develop their research career in a laboratory with a strong emphasis on training and mentorship. There will be opportunities to for the successful appointee to supervise postgraduate students and to apply for their own research funding. A broad skill base, including molecular (qRT-PCR, CRISPR-CAS9 technology) and cellular biology (isolation of mouse primary macrophages, IPSC-derived macvrophages, biochemistry (Immunoprecipitation, Western blotting), immunological assays (ELISA) and mass spectrometry-based proteomics is required.

Eligibility

An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application. The qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Assessment

Applicants should possess a PhD and a strong track record in innate immunity, macrophage biology and inflammation. Experience with the isolation and characterization of mouse primary and human IPSC-derived macrophages are required. Proficiency with molecular biology (qRT-PCR, CRISPR-CAS9), biochemistry (Western blotting, immunoprecipitation, mass spectrometry-based proteomics) basic immunological techniques (ELISA) is a need. Applicants should possess a strong desire to develop a successful and highly-productive research career in immunological research, excellent general research skills, a strong methodological background, excellent writing abilities, and the capacity to work both independently and within a team. Fluency in spoken and written English is essential. Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment

The employment is full time and temporary, two years, with placement at the Institute of Biomedicine. First day of employment as agreed.

For further information:

Please contact Anetta Härtlova, Assistant Professor. Phone: +46 31 786 6241, e-mail: anetta.hartlova@gu.se                                                 

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain:

  • A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
  • A CV including a list of publications
  • Proof of completed PhD
  • Contact details of two references
The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

 

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.