arbetsgivarverket.se

Jobba Statligt

Researcher

  • Ort

    Göteborg

  • Yrkesroll

    Molekylärbiolog

  • Anställning

    Heltid, 6 månader eller längre

  • Lön

    Fast månads- vecko- eller timlön

  • Publicerad

    21 december

  • Sök jobbet senast

    24 januari

Om jobbet

The University of Gothenburg tackles society’s challenges with diverse knowledge. 38 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them. At present, the institute has about 380 employees and approximately 400 million SEK in total assets. The Institute is composed of the following five departments: the Department of Infectious Diseases, the Department of Microbiology and Immunology, the Department of Pathology and Genetics, the Department of Clinical Chemistry and Transfusion Medicine and the Department of Medical Biochemistry and Cell Biology.

Dr. Clausen’s research group is interested in elucidating the molecular mechanism of genome instability and DNA repair. In particular, we are interested in understanding how DNA lesions and mutations are generated and repaired on a genome-wide, strand specific scale at single nucleotide resolution level using CRISPR/Cas9. The group will use interdisciplinary approaches to map and characterize DNA lesions and mutations in yeast, human cells and in patients with genetic diseases or cancer.

Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. Tracking DNA replication in vivo using ribonucleotides. Nat. Struct. Mol. Biol. 2015; 22:185-91. PMID: 25622295.

Berglund AK, Navarrete C, Engqvist MK, Hoberg E, Szilagyi Z, Taylor RW, Gustafsson CM, Falkenberg M, Clausen AR. Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA. PLoS Genet. 2017. 16;13(2):e1006628. PMID: 28207748.

Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A. Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired. Proc Natl Acad Sci U S A. 2017;114(47):12466-12471. PMID: 29109257

Job assignments


Cultivating cells and isolate DNA. Construct DNA libraries for Next-Gen sequencing. Planning, executing and reporting research projects.

Qualifications


The applicant must hold a PhD and have experience in cell- and molecular biology. It is preferred that applicants have experience with Next-Gen sequencing technology and has experience with CRISPR/Cas9.

Employment


The employment is limited (temporary) for 12 months and full-time with placement at the Institute of Biomedicine. First day of employment as agreed.

For further information regarding the position


Please contact Postdoctoral Research Fellow Anders R. Clausen. E-mail: anders.clausen@gu.se

Unions


Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

How to apply


In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain proof of completed PhD.

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

 

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.