arbetsgivarverket.se

Jobba Statligt

Postdoctoral fellow in bioinformatics and antibiotic resistance

  • Ort

    Göteborg

  • Yrkesroll

    Bioinformatiker

  • Anställning

    Heltid, 6 månader eller längre

  • Lön

    Fast månads- vecko- eller timlön

  • Publicerad

    15 augusti

  • Sök jobbet senast

    20 september

Om jobbet

The University of Gothenburg tackles society’s challenges with diverse knowledge. 47 500 students and 6 400 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

24 month full time postdoctoral position within the research group led by Professor Joakim Larsson, Department of Infectious Diseases, Institute for Biomedicine, Sahlgrenska academy at the University of Gothenburg, Sweden. The focus of the research group is on antibiotic resistance development, particularly the role of the external environment. The group consists of 1 professor, 2 associate professors, 5 postdoctoral fellows, 3 PhD students, 1 technician, as well as master students. (http://biomedicine.gu.se/ominst/avd/infektion/forskare/joakim_larsson). Larsson also leads the Centre of Antibiotic Resistance Research at University of Gothenburg (CARe; www.care.gu.se) with over 100 researchers. The group has extensive collaboration with other universities, nationally and internationally. The research is interdisciplinary and has significant funding through e.g. the Swedish Research Councils VR and Formas. 

Subject area description

Most of the resistance genes that cause problems in the clinic today seem to originate from harmless, environmental bacteria. Our group studies the driving forces behind this development, particularly how low levels of antibiotics may affects processes such as mobilization of resistance genes, mutations, horizontal gene transfer, selection and transmission of resistance between environments. In some sub-projects, we study the evolutionary relationship between resistance genes in environmental bacteria and pathogens, and search for new forms of resistance in different environments using both bioinformatic methods as well different large-scale functional screens. A better knowledge about what resistance factors we might face in the clinic tomorrow is valuable to be able to respond rapidly to new threats. We are looking for a postdoc who is interested in taking on the task to explore different environments for novel, mobile resistance genes not yet found in pathogens using modelling, and to characterize these in collaboration with colleagues in the lab. Other research questions involve risks for transmission of resistant bacteria via the environment, as well as risks that pollution with selective agents will favor the evolution of resistance.

Job assignments

The postdoctoral fellow is expected to conduct research with the aim of identifying novel, mobile resistance genes in different environments. Besides identifying and expressing such genes, the work may involve investigating their evolution, function, mobility and presence in different species and environments, in collaboration with e.g. molecular biologists, microbiologists and structural chemists. The research may also involve other aspects regarding the selection, evolution, presence and transmission of antibiotic resistance, as part of other ongoing projects within the research group. One such project deal with risks for transmission of enteric pathogens to workers at sewage treatment plants and close-by residents, using e.g. metagenomics and genomic data of bacteria and microbial communities from water, air and feces. The work also includes authoring/co-authoring scientific publications and presenting research at international scientific conferences.

Eligibility

An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application. 

Assessment

PhD in relevant area, as well as excellent scientific production in relation to the time passed since completing PhD are required. A high degree of independence including extensive experience of bioinformatics analyses of metagenomes and genomes, development and validation of models to identify antibiotic resistance genes, programming in relevant languages (e.g. Python), broad experience of different bioinformatic tools, excellent communicative skills particularly regarding verbal and written scientific English, a developed way of critical thinking, and an ability to work successfully in a group are all additional qualifying criteria. 

For further information:

Please contact Joakim Larsson, professor. E-mail: joakim.larsson@fysiologi.gu.se 

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain:

  • A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
  • A CV including a list of publications
  • Proof of completed PhD
  • Contact details of two references
The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned. 

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.